Narrative:

Aircraft IRU placarded inoperative; #3; dispatched. Remaining #1 and #2 IRU's contained a drift input from unknown source. No warnings or cautions. Navigation checks and verify position message revealed aircraft position off course 6 mi in 1 hour; 16 mi in 2 hours; 60 mi in 3 hours. Drift 67 mi total. ATC agencies advised; flight vectored only after updates failed.

Google
 

Original NASA ASRS Text

Title: AN A300 DISPATCHED WITH 1 IRU MEL'ED EXPERIENCE EXCESSIVE NAV SYS DRIFT RATE RESULTING IN VECTOR NAV.

Narrative: ACFT IRU PLACARDED INOP; #3; DISPATCHED. REMAINING #1 AND #2 IRU'S CONTAINED A DRIFT INPUT FROM UNKNOWN SOURCE. NO WARNINGS OR CAUTIONS. NAV CHKS AND VERIFY POS MESSAGE REVEALED ACFT POS OFF COURSE 6 MI IN 1 HR; 16 MI IN 2 HRS; 60 MI IN 3 HRS. DRIFT 67 MI TOTAL. ATC AGENCIES ADVISED; FLT VECTORED ONLY AFTER UPDATES FAILED.

Data retrieved from NASA's ASRS site as of January 2009 and automatically converted to unabbreviated mixed upper/lowercase text. This report is for informational purposes with no guarantee of accuracy. See NASA's ASRS site for official report.