Narrative:

Center controller cleared us direct peotone (eon) and captain typed in eno. Aircraft turned to navigation to eno. Controller caught us and turned us south. As a pilot, flying mostly on the east coast, eno (kenton) is a frequently used fix. The letters looked correct. Next time, when flying in less frequented airspace, to pay closer attention to the identifiers.

Google
 

Original NASA ASRS Text

Title: CLRED TO EON BUT TYPED ENO INTO THE FMC. A HIGH TECHNOLOGY NAV ERROR.

Narrative: CENTER CTLR CLRED US DIRECT PEOTONE (EON) AND CAPT TYPED IN ENO. ACFT TURNED TO NAV TO ENO. CTLR CAUGHT US AND TURNED US S. AS A PLT, FLYING MOSTLY ON THE E COAST, ENO (KENTON) IS A FREQUENTLY USED FIX. THE LETTERS LOOKED CORRECT. NEXT TIME, WHEN FLYING IN LESS FREQUENTED AIRSPACE, TO PAY CLOSER ATTN TO THE IDENTIFIERS.

Data retrieved from NASA's ASRS site as of July 2007 and automatically converted to unabbreviated mixed upper/lowercase text. This report is for informational purposes with no guarantee of accuracy. See NASA's ASRS site for official report.